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Medication Temperature

Updated over 3 weeks ago

Medications like Semaglutide and Tirzepatide are shipped with ice packs to help protect their stability during transit. Sometimes, patients notice that ice packs have melted or that the package feels warm upon arrival. Here’s what you need to know and the steps to take if this happens.


General Information About Shipping

  • Packed with Ice: Your medication is shipped with ice packs to help keep it cool during transit. The ice packs are designed to absorb heat, so it is expected that they will melt.

  • Temperature Stability: GLP-1 medications are generally stable for short periods, even outside of the refrigerator, but each pharmacy has its own specific stability guidelines.

  • Safe Next Step: Always place your medication in the refrigerator immediately after receiving it.


Steps to Take if Your Medication Feels Warm

  1. Refrigerate Immediately
    As soon as your package arrives, put the vial(s) into your refrigerator—even if the ice packs have melted.

  2. Check for Issues
    Inspect the vial for any visible changes such as discoloration, cloudiness, or leaking. Do not use the medication if you see something unusual.

  3. Document Concerns
    Take clear photos of the medication, its label, and the shipping packaging (including melted ice packs).

  4. Contact Shed Support
    If you’re worried the medication may have been exposed to higher temperatures for too long, reach out to Shed Support. We’ll help you verify your pharmacy’s temperature guidelines and whether your medication is safe to use.


Important Reminder

Because Shed partners with multiple pharmacies, storage and stability guidelines may differ slightly depending on where your prescription is filled. For that reason, Shed Support is the best point of contact if you need specific guidance.


FAQ

Is my medication ruined if it arrives warm?

Not necessarily. These medications are more stable than they may appear, and short periods outside of the fridge usually do not compromise their effectiveness. Always refrigerate immediately and check with Shed Support if you have concerns.

How long can my medication be out of the refrigerator?

Each pharmacy has its own stability guidelines. Shed Support can confirm the specifics for your prescription based on where it was filled.

What should I do if my vial looks different (cloudy, discolored, leaking)?

Do not use the medication. Take photos and contact Shed Support right away so we can coordinate with your pharmacy.

Can Shed replace my medication if it’s been exposed to heat?

Replacements depend on the pharmacy’s review and policies. Shed Support will guide you through next steps if a replacement is needed.

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